p38(MAPK14) Rabbit Polyclonal Antibody

CAT#: TA321327

Anti-MAPK14 (Phospho-Thr180) Rabbit Polyclonal Antibody


 Product Datasheet for 'TA321327'

USD 335.00


Availability*
3 Weeks

Size
    • 100 ul


Product images

Specifications

Product Data
Applications WB, IHC
Recommend Dilution WB: 1:500-1000, IHC: 1:50-100
Reactivity Human; Mouse; Rat
Modifications Phospho-specific
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of threonine 180 (E-M-T(p)-G-Y ) derived from Human MAPK14.
Isotype IgG
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 1mg/ml
Purification Antigen affinity purification
Predicted Protein Size 43kDa
Gene Name mitogen-activated protein kinase 14
Background Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
Synonyms CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA
Reference Data
Protein Families Protein Kinase, Druggable Genome
Protein Pathways MAPK signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Amyotrophic lateral sclerosis (ALS), Epithelial cell signaling in Helicobacter pylori infection
Other products for "MAPK14"
Frequently bought together (2)
Transient overexpression lysate of mitogen-activated protein kinase 14 (MAPK14), transcript variant 1
    • 100 ug

USD 315.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 150.00

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Antibody Performance Guarantee banner
40% off proteins and antibodies
68 Mouse Clones