GLI1 Rabbit Monoclonal Antibody [Clone ID: EPR4523]

CAT#: TA310536

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Rabbit Monoclonal antibody against Gli-1 (GLI1)

 Product Datasheet for 'TA310536'

 Cited in 1 publication.

USD 509.00

In Stock

    • 100 ul

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Product Data
Clone Name EPR4523
Applications IF, IHC, WB
Recommend Dilution WB: 1:1000 - 1:10000; ICC/IF: 1:250 - 1:500; IHC-P: 1:250 - 1:500
Reactivity Human (Does not react with: Mouse, Rat)
Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen A synthetic peptide corresponding to residues in human Gli-1 was used as an immunogen.
Formulation Preservative: 0.01% Sodium azide; Constituents: 40% Glycerol, 0.05% BSA, 59% PBS
Purification Protein A purified
Gene Name GLI family zinc finger 1
Background Gli-1 is a member of the Kruppel family of zinc finger proteins. This transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop (1).
Synonyms GLI
Note Is unsuitable for Flow Cyt or IP.
Reference Data
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

Citations (1)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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