ETS1 Rabbit Monoclonal Antibody [Clone ID: EPR546(2)]

CAT#: TA307238

Rabbit monoclonal antibody against ETS1(clone EPR546(2))

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 Product Datasheet for 'TA307238'

USD 512


Availability*
In Stock

Size
    • 100 ul

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Specifications

Product Data
Clone Name EPR546(2)
Applications WB
Recommend Dilution WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
Reactivity Mouse, Human (Does not react with: Rat)
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide corresponding to residues in human ETS1 was used as an immunogen.
Isotype IgG
Formulation PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Gene Name ETS proto-oncogene 1, transcription factor
Background ETS transcriptions factors, such as ETS1, regulate numerous proteins and are involved in stem cell development, cell senescence and death, and tumorigenesis (1). Furthermore, it regulates the expression of several angiogenic and extracellular matrix remodeling factors promoting an invasive phenotype (2). The conserved ETS domain within ETS1 is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target proteins (2). ETS-1 is expressed in a variety of cells, including endothelial cells, vascular smooth muscle cells and epithelial cells (2).
Synonyms ETS-1|EWSR2|c-ets-1|p54
Note Is unsuitable for ICC,IHC-P or IP.
Reference Data
Protein Families Transcription Factors, Druggable Genome
Protein Pathways Dorso-ventral axis formation, Pathways in cancer, Renal cell carcinoma
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.