PDPN Mouse Monoclonal Antibody [Clone ID: 18H5]

CAT#: DM3500

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PDPN mouse monoclonal antibody, clone 18H5, Supernatant



USD 440.00


Availability*
2 Weeks

Size
    • 200 ul


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Specifications

Product Data
Clone Name 18H5
Applications FC, IF, IHC, IP, WB
Recommended Dilution Flow Cytometry: 1/50.
Immunoprecipitation: 1/50.
Western blot: 1/100.
Immunohistochemistry on Frozen and Paraffin Embedded Sections: 1/50-1/200.
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody will detect Podoplanin on the surface of lymphatic endothelial cells and kidney podocytes by Immunostaining or Immunohistochemistry.
Formulation State: Supernatant
State: Liquid Concentrated Tissue Culture Supernatant
Preservative: 0.09% Sodium Azide
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Background Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a Mr 38,000 membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.
Synonyms Glycoprotein 36, PA2.26 antigen, T1-alpha, Aggrus, PDPN, GP36, PSEC0003, PSEC0025
Reference Data
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