EIF3S3 (EIF3H) (N-term) Rabbit Polyclonal Antibody
EIF3S3 (EIF3H) (N-term) rabbit polyclonal antibody, Aff - Purified
|Recommended Dilution||ELISA: 1/1000.
Western Blot: 1/100 - 1/500.
Immunohistochemistry on paraffin sections: 1/10 - 1/50.
|Immunogen||KLH conjugated synthetic peptide between 69-99 amino acids from the N-terminal region of human EIF3H|
|Specificity||This antibody reacts to EIF3H.|
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.09% (W/V) sodium azide
|Purification||Affinity chromatography on Protein A|
Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
|Stability||Shelf life: one year from despatch.|
|Predicted Protein Size||39930 Da|
|Gene Name||Homo sapiens eukaryotic translation initiation factor 3 subunit H (EIF3H)|
|Background||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.|
|Synonyms||Eukaryotic translation initiation factor 3 subunit H, eIF-3 gamma, eIF3 p40|