Adeno-Associated Virus 2 / AAV2 (Replicase Rep 78, 68, 52, 40) Mouse Monoclonal Antibody [Clone ID: 303.9]
Adeno-Associated Virus 2 / AAV2 (Replicase Rep 78, 68, 52, 40) mouse monoclonal antibody, clone 303.9, Aff - Purified
|Recommended Dilution||Immunoblotting: 1/50-1/100.|
|Immunogen||Recombinant AAV-2 Rep 78 protein, N-terminally truncated by 171 aa|
|Specificity||This antibody reacts with Replicase proteins (Rep78, Rep68, Rep52 and Rep40) of Human AAV-2-infected cells.
Cross-reactivity with AAV serotypes 1, 3, 4, 5, and 6.
A weak cross-reactivity is seen in some Human cell lines.
|Formulation||Final solution contains 0.09% Sodium Azide, 0.5% BSA in PBS buffer, pH 7.4
State: Aff - Purified
State: Lyophilized purified IgG fraction
|Reconstitution Method||Restore in 1 ml distilled water|
|Purification||Affinity Chromatography on Protein A|
|Storage||Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Background||Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Serotype 2 (AAV2) has been the most extensively examined so far. AAV2 presents natural tropism towards skeletal muscles, neurons, vascular smooth muscle cells and hepatocytes.|