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Target Symbol
- CD44 (8)
- EGFR (7)
- BRCA2 (6)
- FIBRONECTIN (6)
- BRCA1 (5)
- TENASCIN C (5)
- CUX1 (3)
- EVI1 (3)
- ABCG2 (2)
- BAX (2)
- CD30 (2)
- CD62P (2)
- CYCLIN A2 (2)
- E CADHERIN (2)
- ENOS (2)
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- HDAC2 (2)
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- IL1RA (2)
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- SOMATOSTATIN RECEPTOR 2 (2)
- XPC (2)
- AAMP (1)
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- ALDEHYDE DEHYDROGENASE 10 (1)
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- CARBONIC ANHYDRASE IX (1)
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- CDC25C (1)
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Knockout (KO) Validation
Assay Types
Families
- Druggable Genome (329)
- Transmembrane (122)
- Transcription Factors (73)
- Secreted Protein (67)
- ES Cell Differentiation/IPS (64)
- Protein Kinase (38)
- Stem cell - Pluripotency (33)
- Adult stem cells (18)
- Cancer stem cells (18)
- Embryonic stem cells (14)
- Protease (13)
- GPCR (10)
- Stem cell relevant signaling - DSL/Notch pathway (9)
- Phosphatase (8)
- Stem cell relevant signaling - JAK/STAT signaling pathway (8)
- Induced pluripotent stem cells (4)
- Ion Channels: Other (4)
- Stem cell relevant signaling - Wnt Signaling pathway (3)
- Ion Channels: Glutamate Receptors (2)
- Ion Channels: Sodium (2)
- Ion Channels: Transient receptor potential (1)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (1)
Pathways
- Pathways in cancer (72)
- Focal adhesion (33)
- MAPK signaling pathway (30)
- Cytokine-cytokine receptor interaction (28)
- Metabolic pathways (26)
- Regulation of actin cytoskeleton (26)
- ECM-receptor interaction (24)
- Endocytosis (21)
- Pancreatic cancer (21)
- Colorectal cancer (20)
- Neurotrophin signaling pathway (20)
- Prostate cancer (20)
- Small cell lung cancer (19)
- Epithelial cell signaling in Helicobacter pylori infection (16)
- ErbB signaling pathway (16)
- Ubiquitin mediated proteolysis (16)
- Cell cycle (15)
- Chronic myeloid leukemia (15)
- Endometrial cancer (15)
- Insulin signaling pathway (15)
- Melanoma (15)
- Apoptosis (14)
- Bladder cancer (14)
- Chemokine signaling pathway (14)
- Adherens junction (13)
- Calcium signaling pathway (13)
- Glioma (13)
- GnRH signaling pathway (13)
- Hematopoietic cell lineage (13)
- Homologous recombination (12)
- p53 signaling pathway (12)
- Jak-STAT signaling pathway (11)
- Non-small cell lung cancer (11)
- Acute myeloid leukemia (10)
- Adipocytokine signaling pathway (10)
- Axon guidance (10)
- Gap junction (10)
- Neuroactive ligand-receptor interaction (10)
- Nucleotide excision repair (10)
- Renal cell carcinoma (10)
- Toll-like receptor signaling pathway (10)
- B cell receptor signaling pathway (9)
- Progesterone-mediated oocyte maturation (9)
- T cell receptor signaling pathway (9)
- Cell adhesion molecules (CAMs) (8)
- Dorso-ventral axis formation (8)
- Huntington's disease (8)
- Natural killer cell mediated cytotoxicity (8)
- Type II diabetes mellitus (8)
- Wnt signaling pathway (8)
- ABC transporters (7)
- Alzheimer's disease (7)
- Amyotrophic lateral sclerosis (ALS) (7)
- Glycolysis / Gluconeogenesis (7)
- Leukocyte transendothelial migration (7)
- NOD-like receptor signaling pathway (7)
- Basal cell carcinoma (6)
- Long-term depression (6)
- Melanogenesis (6)
- Notch signaling pathway (6)
- RIG-I-like receptor signaling pathway (6)
- Tight junction (6)
- VEGF signaling pathway (6)
- Arginine and proline metabolism (5)
- Complement and coagulation cascades (5)
- Cytosolic DNA-sensing pathway (5)
- DNA replication (5)
- Fc epsilon RI signaling pathway (5)
- Fc gamma R-mediated phagocytosis (5)
- Hypertrophic cardiomyopathy (HCM) (5)
- Mismatch repair (5)
- Oocyte meiosis (5)
- Prion diseases (5)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (4)
- Base excision repair (4)
- Dilated cardiomyopathy (4)
- Hedgehog signaling pathway (4)
- Long-term potentiation (4)
- Non-homologous end-joining (4)
- Purine metabolism (4)
- Pyrimidine metabolism (4)
- mTOR signaling pathway (4)
- Alanine (3)
- Amino sugar and nucleotide sugar metabolism (3)
- Histidine metabolism (3)
- Lysosome (3)
- PPAR signaling pathway (3)
- Pathogenic Escherichia coli infection (3)
- Pyruvate metabolism (3)
- Spliceosome (3)
- TGF-beta signaling pathway (3)
- Thyroid cancer (3)
- Tryptophan metabolism (3)
- Tyrosine metabolism (3)
- Valine (3)
- aspartate and glutamate metabolism (3)
- leucine and isoleucine degradation (3)
- Allograft rejection (2)
- Ascorbate and aldarate metabolism (2)
- Autoimmune thyroid disease (2)
- Butanoate metabolism (2)
- Citrate cycle (TCA cycle) (2)
- Cysteine and methionine metabolism (2)
- Drug metabolism - cytochrome P450 (2)
- Fatty acid metabolism (2)
- Glycerolipid metabolism (2)
- Graft-versus-host disease (2)
- Limonene and pinene degradation (2)
- Lysine degradation (2)
- Pentose phosphate pathway (2)
- Phenylalanine metabolism (2)
- Propanoate metabolism (2)
- Renin-angiotensin system (2)
- Type I diabetes mellitus (2)
- Viral myocarditis (2)
- beta-Alanine metabolism (2)
- Arachidonic acid metabolism (1)
- Caffeine metabolism (1)
- Cardiac muscle contraction (1)
- Drug metabolism - other enzymes (1)
- Fructose and mannose metabolism (1)
- Glutathione metabolism (1)
- Glycine (1)
- Metabolism of xenobiotics by cytochrome P450 (1)
- N-Glycan biosynthesis (1)
- Nicotinate and nicotinamide metabolism (1)
- Nitrogen metabolism (1)
- Oxidative phosphorylation (1)
- Parkinson's disease (1)
- Phenylalanine (1)
- Proteasome (1)
- RNA degradation (1)
- RNA polymerase (1)
- Riboflavin metabolism (1)
- SNARE interactions in vesicular transport (1)
- Starch and sucrose metabolism (1)
- Systemic lupus erythematosus (1)
- Taste transduction (1)
- Ubiquinone and other terpenoid-quinone biosynthesis (1)
- Vascular smooth muscle contraction (1)
- Vibrio cholerae infection (1)
- Vitamin B6 metabolism (1)
- serine and threonine metabolism (1)
- tyrosine and tryptophan biosynthesis (1)