FASTK (NM_006712) Human Recombinant Protein

CAT#: TP762537

Purified recombinant protein of Human Fas-activated serine/threonine kinase (FASTK), transcript variant 1, 50ug

Product Images

Coomassie blue staining of purified FASTK protein (Cat #TP762537). The protein was produced from E.coli.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of FASTK
• Tag: N-GST and C-HIS
• Predicted MW: 61.1 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_006703
• Locus ID: 10922
• UniProt ID: Q14296, A0A090N8Z7
• Cytogenetics: 7q36.1
• Refseq Size: 1885
• Refseq ORF: 1647
• Synonyms: FAST
• Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Protein Kinase