beta 2 Microglobulin (B2M) (NM_004048) Human Recombinant Protein

CAT#: TP750209

Purified recombinant protein of human beta-2-microglobulin(B2M), Ile21-Met119, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein B2M was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MHHHHHHIQR TPKIQVYSRH PAENGKSNFL NCYVSGFHPS DIEVDLLKNG ERIEKVEHSD
  LSFSKDWSFY LLYYTEFTPT EKDEYACRVN HVTLSQPKIV KWDRDM
• Tag: N-His
• Predicted MW: 12.7 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_004039
• Locus ID: 567
• UniProt ID: P61769
• Cytogenetics: 15q21.1
• Synonyms: IMD43
• Summary: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Antigen processing and presentation