RSPO3 (NM_032784) Human Recombinant Protein
CAT#: TP721065L
Purified recombinant protein of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Gln22-His272
|
Tag | C-Fc&His |
Predicted MW | 56.3 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_116173 |
Locus ID | 84870 |
UniProt ID | Q9BXY4 |
Cytogenetics | 6q22.33 |
Refseq Size | 4583 |
Refseq ORF | 816 |
Synonyms | CRISTIN1; PWTSR; THSD2 |
Summary | This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013] |
Protein Families | Druggable Genome, Secreted Protein |
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