Calcitonin (CALCA) (NM_001033952) Human Recombinant Protein

CAT#: TP720989

Purified recombinant protein of Human calcitonin-related polypeptide alpha (CALCA), transcript variant 2

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Tyr58-Asn141
• Tag: C-His
• Predicted MW: 10.5 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001029124
• Locus ID: 796
• UniProt ID: P01258
• Cytogenetics: 11p15.2
• Refseq Size: 816
• Refseq ORF: 423
• Synonyms: CALC1; CGRP; CGRP-alpha; CGRP-I; CGRP1; CT; KC; PCT
• Summary: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
• Protein Families: Druggable Genome, Secreted Protein