CD61 (ITGB3) (NM_000212) Human Recombinant Protein

CAT#: TP321606

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Recombinant protein of human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3)


 Product Datasheet for 'TP321606'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 84.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000203
Locus ID 3690
Refseq Size 4894
Cytogenetics 17q21.32
Refseq ORF 2364
Synonyms BDPLT2; BDPLT16; CD61; GP3A; GPIIIa; GT
Summary The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton

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