CD61 (ITGB3) (NM_000212) Human Recombinant Protein

CAT#: TP321606

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Recombinant protein of human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3)


 Product Datasheet for 'TP321606'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC221606. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 84.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000203
Locus ID 3690
Refseq Size 4894
Cytogenetics 17q21.32
Refseq ORF 2364
Synonyms BDPLT2; BDPLT16; CD61; GP3A; GPIIIa; GT
Summary The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton

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