CD61 (ITGB3) (NM_000212) Human Recombinant Protein

CAT#: TP762346

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Purified recombinant protein of Human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3), Ser536-Asp718, with N-terminal His tag, expressed in E.coli, 50ug



  View other "ITGB3" proteins (4)

USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3), Ser536-Asp718, with N-terminal His tag, expressed in E.coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding the region(Ser536-Asp718) of CD61
Tag N-His
Predicted MW 20.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000203
Locus ID 3690
UniProt ID P05106
Cytogenetics 17q21.32
Refseq Size 4894
Refseq ORF 2364
Synonyms BDPLT2; BDPLT16; CD61; GP3A; GPIIIa; GT
Summary The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton

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