Ccl2 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN302782RB
Ccl2 - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | Ccl2 |
Locus ID | 20296 |
Components |
KN302782G1, Ccl2 gRNA vector 1 in pCas-Guide CRISPR vector KN302782G2, Ccl2 gRNA vector 2 in pCas-Guide CRISPR vector KN302782RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_011333 |
UniProt ID | P10148 |
Synonyms | AI323594; HC11; JE; MCAF; MCP-1; MCP1; Scya2; Sigje; SMC-CF |
Summary | This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015] |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
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KN302782 | Ccl2 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN302782BN | Ccl2 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN302782LP | Ccl2 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN502782 | Ccl2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA203799 | Ccl2 CRISPRa kit - CRISPR gene activation of mouse chemokine (C-C motif) ligand 2 |
USD 1,657.00 |
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