C19orf80 (ANGPTL8) Human Gene Knockout Kit (CRISPR)

CAT#: KN218000BN

C19orf80 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: C19orf80
• Locus ID: 55908
• Components:

  KN218000G1, C19orf80 gRNA vector 1 in pCas-Guide CRISPR vector

  KN218000G2, C19orf80 gRNA vector 2 in pCas-Guide CRISPR vector

  KN218000BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_018687
• UniProt ID: Q6UXH0
• Synonyms: C19orf80; PRO1185; PVPA599; RIFL; TD26
• Summary: Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (By similarity).[UniProtKB/Swiss-Prot Function]