Mouse Adcy5 activation kit by CRISPRa

CAT#: GA213677

Adcy5 CRISPRa kit - CRISPR gene activation of mouse adenylate cyclase 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Adcy5
• Locus ID: 224129
• Kit Components:

  GA213677G1, Adcy5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA213677G2, Adcy5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA213677G3, Adcy5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012765
• UniProt ID: P84309
• Synonyms: Ac5; AW121902
• Summary: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion.[UniProtKB/Swiss-Prot Function]