Mouse Coq6 activation kit by CRISPRa

CAT#: GA213493

Coq6 CRISPRa kit - CRISPR gene activation of mouse coenzyme Q6 monooxygenase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Coq6
• Locus ID: 217707
• Kit Components:

  GA213493G1, Coq6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA213493G2, Coq6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA213493G3, Coq6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_172582
• UniProt ID: Q8R1S0
• Synonyms: 5930427M12Rik; AW742344
• Summary: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.[UniProtKB/Swiss-Prot Function]