Mouse Mboat7 activation kit by CRISPRa

CAT#: GA210774

Mboat7 CRISPRa kit - CRISPR gene activation of mouse membrane bound O-acyltransferase domain containing 7

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Mboat7
• Locus ID: 77582
• Kit Components:

  GA210774G1, Mboat7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210774G2, Mboat7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210774G3, Mboat7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_029934
• UniProt ID: Q8CHK3
• Synonyms: 5730589L02Rik; BB1; Leng4; Lpiat; Lpiat1; mBB1
• Summary: Acyltransferase which contributes to the regulation of free arachidonic acid (AA) in the cell through the remodeling of phospholipids. Mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor (PubMed:23097495). Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (By similarity). Required for cortical lamination during brain development (PubMed:23097495).[UniProtKB/Swiss-Prot Function]