Mouse Pdcd10 activation kit by CRISPRa

CAT#: GA205961

Pdcd10 CRISPRa kit - CRISPR gene activation of mouse programmed cell death 10

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Pdcd10
• Locus ID: 56426
• Kit Components:

  GA205961G1, Pdcd10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205961G2, Pdcd10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205961G3, Pdcd10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019745
• UniProt ID: Q8VE70
• Synonyms: 2410003B13Rik; Ccm3; Tfa15; Tfar15
• Summary: Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex (By similarity). Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity).[UniProtKB/Swiss-Prot Function]