Mouse Pcbp2 activation kit by CRISPRa

CAT#: GA203113

Pcbp2 CRISPRa kit - CRISPR gene activation of mouse poly(rC) binding protein 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Pcbp2
• Locus ID: 18521
• Kit Components:

  GA203113G1, Pcbp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203113G2, Pcbp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203113G3, Pcbp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001103165, NM_001103166, NM_001174073, NM_011042
• UniProt ID: Q61990
• Synonyms: alphaCP-2; AW412548; Hnrpx
• Summary: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation (By similarity).[UniProtKB/Swiss-Prot Function]