Mouse Nfe2l2 activation kit by CRISPRa

CAT#: GA202876

Nfe2l2 CRISPRa kit - CRISPR gene activation of mouse nuclear factor, erythroid derived 2, like 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Nfe2l2
• Locus ID: 18024
• Kit Components:

  GA202876G1, Nfe2l2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202876G2, Nfe2l2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202876G3, Nfe2l2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010902, NR_132727
• UniProt ID: Q60795
• Synonyms: Nrf2
• Summary: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. [provided by RefSeq, Sep 2015]