Human CD200R (CD200R1) activation kit by CRISPRa

CAT#: GA115145

CD200R1 CRISPRa kit - CRISPR gene activation of human CD200 receptor 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CD200R1
• Locus ID: 131450
• Kit Components:

  GA115145G1, CD200R gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115145G2, CD200R gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115145G3, CD200R gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138806, NM_138939, NM_138940, NM_170780
• UniProt ID: Q8TD46
• Synonyms: CD200R; HCRTR2; MOX2R; OX2R
• Summary: This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]