Human CCL28 activation kit by CRISPRa

CAT#: GA111190

CCL28 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 28

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CCL28
• Locus ID: 56477
• Kit Components:

  GA111190G1, CCL28 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111190G2, CCL28 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111190G3, CCL28 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301873, NM_001301874, NM_001301875, NM_019846, NM_148672
• UniProt ID: Q9NRJ3
• Synonyms: CCK1; MEC; SCYA28
• Summary: This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]