Human PHF7 activation kit by CRISPRa

CAT#: GA109858

PHF7 CRISPRa kit - CRISPR gene activation of human PHD finger protein 7

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PHF7
• Locus ID: 51533
• Kit Components:

  GA109858G1, PHF7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109858G2, PHF7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109858G3, PHF7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278221, NM_001321126, NM_001321127, NM_016483, NM_173341
• UniProt ID: Q9BWX1
• Synonyms: HSPC045; HSPC226; NYD-SP6
• Summary: Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. This gene is expressed in the testis in Sertoli cells but not germ cells. The protein encoded by this gene contains plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. The protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]