Human HTF9C (TRMT2A) activation kit by CRISPRa

CAT#: GA108979

TRMT2A CRISPRa kit - CRISPR gene activation of human tRNA methyltransferase 2 homolog A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TRMT2A
• Locus ID: 27037
• Kit Components:

  GA108979G1, HTF9C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108979G2, HTF9C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108979G3, HTF9C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001257994, NM_001331039, NM_022727, NM_182984
• UniProt ID: Q8IZ69
• Synonyms: HTF9C
• Summary: The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]