Human TCEAL1 activation kit by CRISPRa

CAT#: GA106225

TCEAL1 CRISPRa kit - CRISPR gene activation of human transcription elongation factor A like 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TCEAL1
• Locus ID: 9338
• Kit Components:

  GA106225G1, TCEAL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106225G2, TCEAL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106225G3, TCEAL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001006639, NM_001006640, NM_004780
• UniProt ID: Q15170
• Synonyms: p21; pp21; SIIR; WEX9
• Summary: This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]