Human Tripeptidyl peptidase II (TPP2) activation kit by CRISPRa

CAT#: GA104958

TPP2 CRISPRa kit - CRISPR gene activation of human tripeptidyl peptidase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TPP2
• Locus ID: 7174
• Kit Components:

  GA104958G1, Tripeptidyl peptidase II gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104958G2, Tripeptidyl peptidase II gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104958G3, Tripeptidyl peptidase II gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003291, NM_001330588, N27441, NR_160411, NM_001367947
• UniProt ID: P29144
• Synonyms: TPP-2
• Summary: This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008]