Human CALML3 activation kit by CRISPRa

CAT#: GA100564

CALML3 CRISPRa kit - CRISPR gene activation of human calmodulin like 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CALML3
• Locus ID: 810
• Kit Components:

  GA100564G1, CALML3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100564G2, CALML3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100564G3, CALML3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005185
• UniProt ID: P27482
• Synonyms: CLP
• Summary: May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates.[UniProtKB/Swiss-Prot Function]