RRAD (NM_001128850) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC225433L2V

Lenti ORF particles, RRAD (mGFP-tagged) - Human Ras-related associated with diabetes (RRAD), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: RRAD
• Synonyms: RAD; RAD1; REM3
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001128850
• ORF Size: 924 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC225433).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001128850.1, NP_001122322.1
• RefSeq ORF: 927 bp
• Locus ID: 6236
• UniProt ID: P55042
• Cytogenetics: 16q22.1
• MW: 33.1 kDa
• Gene Summary: May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.[UniProtKB/Swiss-Prot Function]