KCC2 (SLC12A5) (NM_020708) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223680L1V

Lenti ORF particles, SLC12A5 (Myc-DDK tagged) - Human solute carrier family 12 (potassium/chloride transporter), member 5 (SLC12A5), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: KCC2
• Synonyms: DEE34; EIEE34; EIG14; hKCC2; KCC2
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_020708
• ORF Size: 3348 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223680).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020708.3
• RefSeq Size: 6059 bp
• RefSeq ORF: 3351 bp
• Locus ID: 57468
• UniProt ID: Q9H2X9
• Cytogenetics: 20q13.12
• Protein Families: Transmembrane
• MW: 123.3 kDa
• Gene Summary: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008]