NANOS3 (NM_001098622) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221867L4V

Lenti ORF particles, NANOS3 (mGFP-tagged) - Human nanos homolog 3 (Drosophila) (NANOS3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: NANOS3
• Synonyms: NANOS1L; NOS3; ZC2HC12C
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001098622
• ORF Size: 576 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221867).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001098622.1, NP_001092092.1
• RefSeq Size: 946 bp
• RefSeq ORF: 579 bp
• Locus ID: 342977
• UniProt ID: P60323
• Cytogenetics: 19p13.12
• MW: 20.5 kDa
• Gene Summary: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.[UniProtKB/Swiss-Prot Function]