SOAT 2 (SOAT2) (NM_003578) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221499L4V

Lenti ORF particles, SOAT2 (mGFP-tagged) - Human sterol O-acyltransferase 2 (SOAT2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SOAT 2
• Synonyms: ACACT2; ACAT2; ARGP2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_003578
• ORF Size: 1566 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221499).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003578.2
• RefSeq Size: 2073 bp
• RefSeq ORF: 1569 bp
• Locus ID: 8435
• UniProt ID: O75908
• Cytogenetics: 12q13.13
• Protein Families: Transmembrane
• Protein Pathways: Steroid biosynthesis
• MW: 59.8 kDa
• Gene Summary: Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]