Monoacylglycerol Lipase (MGLL) (NM_007283) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218358L2V

Lenti ORF particles, MGLL (mGFP-tagged) - Human monoglyceride lipase (MGLL), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Monoacylglycerol Lipase
• Synonyms: HU-K5; HUK5; MAGL; MGL
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_007283
• ORF Size: 939 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218358).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007283.5
• RefSeq Size: 4617 bp
• RefSeq ORF: 942 bp
• Locus ID: 11343
• UniProt ID: Q99685
• Cytogenetics: 3q21.3
• Domains: abhydrolase
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Glycerolipid metabolism, Metabolic pathways
• MW: 34.1 kDa
• Gene Summary: This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]