CREM (NM_182720) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217789L3V

Lenti ORF particles, CREM (Myc-DDK tagged) - Human cAMP responsive element modulator (CREM), transcript variant 7, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CREM
• Synonyms: CREM-2; hCREM-2; ICER
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_182720
• ORF Size: 324 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217789).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_182720.1
• RefSeq Size: 1955 bp
• RefSeq ORF: 327 bp
• Locus ID: 1390
• UniProt ID: Q03060
• Cytogenetics: 10p11.21
• Protein Families: Druggable Genome, Transcription Factors
• MW: 11.9 kDa
• Gene Summary: This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]