TRIM58 (NM_015431) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217706L2V

Lenti ORF particles, TRIM58 (mGFP-tagged) - Human tripartite motif containing 58 (TRIM58), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TRIM58
• Synonyms: BIA2
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_015431
• ORF Size: 1458 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217706).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015431.2, NP_056246.2
• RefSeq Size: 2594 bp
• RefSeq ORF: 1461 bp
• Locus ID: 25893
• UniProt ID: Q8NG06
• Cytogenetics: 1q44
• Domains: zf-B_box, RING, SPRY, PRY
• Protein Families: Druggable Genome
• MW: 54.6 kDa
• Gene Summary: E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.[UniProtKB/Swiss-Prot Function]