FISH (SH3PXD2A) (NM_014631) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217487L4V

Lenti ORF particles, SH3PXD2A (mGFP-tagged) - Human SH3 and PX domains 2A (SH3PXD2A), 200ul, >10^7 TU/mL

Product Images

RC217487L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC217487L4V particle to overexpress human SH3PXD2A-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: FISH
• Synonyms: FISH; SH3MD1; TKS5
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_014631
• ORF Size: 3315 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217487).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014631.2, NP_055446.2
• RefSeq Size: 11264 bp
• RefSeq ORF: 3318 bp
• Locus ID: 9644
• UniProt ID: Q5TCZ1
• Cytogenetics: 10q24.33
• MW: 121.7 kDa
• Gene Summary: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.[UniProtKB/Swiss-Prot Function]