UGT2A1 (NM_006798) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC217262L4V
- LentiORF®
Lenti ORF particles, UGT2A1 (mGFP-tagged) - Human UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
AAV Particle: DDK
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | UGT2A1 |
Synonyms | UDPGT2A1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_006798 |
ORF Size | 1581 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC217262).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006798.1, NP_006789.1 |
RefSeq Size | 1766 bp |
RefSeq ORF | 1584 bp |
Locus ID | 10941 |
UniProt ID | Q9Y4X1 |
Cytogenetics | 4q13.3 |
Protein Families | Transmembrane |
Protein Pathways | Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism |
MW | 59.7 kDa |
Gene Summary | The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms. [provided by RefSeq, Jul 2014] |
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