PRELP (NM_002725) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC215731L4V

Lenti ORF particles, PRELP (mGFP-tagged) - Human proline/arginine-rich end leucine-rich repeat protein (PRELP), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PRELP
• Synonyms: MST161; MSTP161; SLRR2A
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_002725
• ORF Size: 1146 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215731).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002725.3
• RefSeq Size: 5833 bp
• RefSeq ORF: 1149 bp
• Locus ID: 5549
• UniProt ID: P51888
• Cytogenetics: 1q32.1
• Domains: LRRNT, LRR, LRR_TYP, LRR_PS
• Protein Families: Secreted Protein
• MW: 43.81 kDa
• Gene Summary: The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]