ADAM10 (NM_001110) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC215457L4V

Lenti ORF particles, ADAM10 (mGFP-tagged)-Human ADAM metallopeptidase domain 10 (ADAM10), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: ADAM10
• Synonyms: AD10; AD18; CD156c; CDw156; HsT18717; kuz; MADM; RAK
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001110
• ORF Size: 2244 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215457).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001110.2
• RefSeq Size: 3927 bp
• RefSeq ORF: 2247 bp
• Locus ID: 102
• UniProt ID: O14672
• Cytogenetics: 15q21.3
• Domains: Reprolysin, DISIN
• Protein Families: Druggable Genome, Protease, Transmembrane
• Protein Pathways: Alzheimer's disease, Epithelial cell signaling in Helicobacter pylori infection
• MW: 84 kDa
• Gene Summary: Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016]