CMA1 (NM_001836) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214873L3V

Lenti ORF particles, CMA1 (Myc-DDK tagged) - Human chymase 1, mast cell (CMA1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CMA1
• Synonyms: chymase; CYH; MCT1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001836
• ORF Size: 741 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214873).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001836.1
• RefSeq Size: 744 bp
• RefSeq ORF: 744 bp
• Locus ID: 1215
• UniProt ID: P23946
• Cytogenetics: 14q12
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Renin-angiotensin system
• MW: 27.1 kDa
• Gene Summary: This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]