Neurotrophin 3 (NTF3) (NM_002527) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC214226L4V

Lenti ORF particles, NTF3 (mGFP-tagged) - Human neurotrophin 3 (NTF3), transcript variant 2, 200ul, >10^7 TU/mL

Product Images

RC214226L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC214226L4V particle to overexpress human NTF3-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Neurotrophin 3
• Synonyms: HDNF; NGF-2; NGF2; NT-3; NT3
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_002527
• ORF Size: 771 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214226).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002527.3
• RefSeq Size: 1182 bp
• RefSeq ORF: 774 bp
• Locus ID: 4908
• UniProt ID: P20783
• Cytogenetics: 12p13.31
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Neurotrophin signaling pathway
• MW: 29.4 kDa
• Gene Summary: The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]