GUCY2C (NM_004963) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC213901L3V

Lenti ORF particles, GUCY2C (Myc-DDK tagged) - Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GUCY2C
• Synonyms: DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_004963
• ORF Size: 3219 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213901).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004963.1
• RefSeq Size: 3745 bp
• RefSeq ORF: 3222 bp
• Locus ID: 2984
• UniProt ID: P25092
• Cytogenetics: 12p12.3
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Purine metabolism
• MW: 123.2 kDa
• Gene Summary: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]