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DIAPH1 (NM_001079812) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC213517L1V
- LentiORF®
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Lenti ORF particles, DIAPH1 (Myc-DDK tagged) - Human diaphanous homolog 1 (Drosophila) (DIAPH1), transcript variant 2, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro mGFP mGFP w/ Puro
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USD 365.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
| Tag | Myc-DDK |
| Symbol | DIAPH1 |
| Synonyms | DFNA1; DIA1; DRF1; hDIA1; LFHL1; SCBMS |
| Mammalian Cell Selection | None |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_001079812 |
| ORF Size | 3786 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC213517).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001079812.1 |
| RefSeq Size | 5777 bp |
| RefSeq ORF | 3792 bp |
| Locus ID | 1729 |
| UniProt ID | O60610 |
| Cytogenetics | 5q31.3 |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Focal adhesion, Regulation of actin cytoskeleton |
| MW | 140.2 kDa |
| Gene Summary | This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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