AP1B1 (NM_145730) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212913L3V

Lenti ORF particles, AP1B1 (Myc-DDK-tagged)-Human adaptor-related protein complex 1, beta 1 subunit (AP1B1), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: AP1B1
• Synonyms: ADTB1; AP105A; BAM22; CLAPB2; KIDAR
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_145730
• ORF Size: 2817 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212913).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_145730.2, NP_663782.2
• RefSeq Size: 4164 bp
• RefSeq ORF: 2820 bp
• Locus ID: 162
• UniProt ID: Q10567
• Cytogenetics: 22q12.2
• Domains: Adaptin_N, Alpha_adaptinC2
• Protein Pathways: Lysosome
• MW: 103.5 kDa
• Gene Summary: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]