Cystatin C(CST3) (NM_000099) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC210730L2V
- LentiORF®
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Lenti ORF particles, CST3 (mGFP-tagged) - Human cystatin C (CST3), 200ul, >10^7 TU/mL
Product images

Specifications
Product Data | |
Product Name | Cystatin C(CST3) (NM_000099) Human Tagged ORF Clone Lentiviral Particle |
Symbol | CST3 |
Synonyms | ARMD11; HEL-S-2 |
Vector | pLenti-C-mGFP |
ACCN | NM_000099 |
ORF Size | 438 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC210730).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000099.2, NP_000090 |
RefSeq Size | 818 |
RefSeq ORF | 441 |
Locus ID | 1471 |
Cytogenetics | 20p11.21 |
Domains | CY |
Protein Families | ES Cell Differentiation/IPS, Transmembrane, Druggable Genome |
MW | 15.8 kDa |
Gene Summary | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein. [provided by RefSeq, Nov 2014]. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
cDNA Clone Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC110862 | CST3 (untagged)-Human cystatin C (CST3) |
USD 300.00 |
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RC210730L1 | Lenti ORF clone of Human cystatin C (CST3) , Myc-DDK-tagged |
USD 620.00 |
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RC210730L1V | Lenti ORF particles, CST3 (Myc-DDK tagged) - Human cystatin C (CST3) , 200ul, >10^7 TU/mL |
USD 830.00 |
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RG210730 | CST3 (GFP-tagged) - Human cystatin C (CST3) |
USD 460.00 |
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RC210730L3 | Lenti ORF clone of Human cystatin C (CST3) , Myc-DDK-tagged |
USD 620.00 |
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RC210730L4V | Lenti ORF particles, CST3 (mGFP-tagged) - Human cystatin C (CST3), 200ul, >10^7 TU/mL |
USD 930.00 |
|
RC210730 | CST3 (Myc-DDK-tagged)-Human cystatin C (CST3) |
USD 98.00 |
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RC210730L2 | Lenti ORF clone of Human cystatin C (CST3), mGFP tagged |
USD 680.00 |
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RC210730L3V | Lenti ORF particles, CST3 (Myc-DDK tagged) - Human cystatin C (CST3) , 200ul, >10^7 TU/mL |
USD 830.00 |
|
RC210730L4 | Lenti ORF clone of Human cystatin C (CST3), mGFP tagged |
USD 680.00 |