VPS35 (NM_018206) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210597L4V

Lenti ORF particles, VPS35 (mGFP-tagged) - Human vacuolar protein sorting 35 homolog (S. cerevisiae) (VPS35), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: VPS35
• Synonyms: MEM3; PARK17
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_018206
• ORF Size: 2388 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210597).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018206.3
• RefSeq Size: 3298 bp
• RefSeq ORF: 2391 bp
• Locus ID: 55737
• UniProt ID: Q96QK1
• Cytogenetics: 16q11.2
• Domains: Vps35
• MW: 91.7 kDa
• Gene Summary: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]