TIM 3 (HAVCR2) (NM_032782) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209440L1V

  • LentiORF®

Lenti ORF particles, HAVCR2 (Myc-DDK tagged) - Human hepatitis A virus cellular receptor 2 (HAVCR2), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro

AAV Particle: DDK


Biosafety Sheet

Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50

USD 850.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol TIM 3
Synonyms CD366; HAVcr-2; KIM-3; SPTCL; Tim-3; TIM3; TIMD-3; TIMD3
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_032782
ORF Size 903 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC209440).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_032782.3
RefSeq Size 2448 bp
RefSeq ORF 906 bp
Locus ID 84868
UniProt ID Q8TDQ0
Cytogenetics 5q33.3
Domains IG
Protein Families Druggable Genome, Transmembrane
MW 33.4 kDa
Gene Summary The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

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