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NAGLU (NM_000263) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC208600L1V
- LentiORF®
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Lenti ORF particles, NAGLU (Myc-DDK tagged) - Human N-acetylglucosaminidase, alpha (NAGLU), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro mGFP mGFP w/ Puro
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USD 365.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
| Tag | Myc-DDK |
| Symbol | NAGLU |
| Synonyms | CMT2V; MPS-IIIB; MPS3B; NAG; UFHSD |
| Mammalian Cell Selection | None |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_000263 |
| ORF Size | 2229 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208600).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000263.3 |
| RefSeq Size | 2798 bp |
| RefSeq ORF | 2232 bp |
| Locus ID | 4669 |
| UniProt ID | P54802 |
| Cytogenetics | 17q21.2 |
| Domains | NAGLU |
| Protein Families | Druggable Genome |
| Protein Pathways | Glycosaminoglycan degradation, Lysosome, Metabolic pathways |
| MW | 82.27 kDa |
| Gene Summary | This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq, Jul 2008] |
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