MTHFR (NM_005957) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208588L4V

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  • LentiORF®

Lenti ORF particles, MTHFR (mGFP-tagged) - Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR), 200ul, >10^7 TU/mL



USD 1,020.00


Availability*
6 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol MTHFR
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_005957
ORF Size 1968 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC208588).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_005957.2, NP_005948.2
RefSeq Size 6099 bp
RefSeq ORF 1971 bp
Locus ID 4524
UniProt ID P42898
Cytogenetics 1p36.22
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Methane metabolism, One carbon pool by folate
MW 74.4 kDa
Gene Summary The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.