Thrombomodulin (THBD) (NM_000361) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207598L3V

Lenti ORF particles, THBD (Myc-DDK-tagged)-Human thrombomodulin (THBD), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: THBD
• Synonyms: AHUS6; BDCA-3; BDCA3; CD141; THPH12; THRM; TM
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_000361
• ORF Size: 1725 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207598).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000361.2
• RefSeq Size: 4048 bp
• RefSeq ORF: 1728 bp
• Locus ID: 7056
• UniProt ID: P07204
• Cytogenetics: 20p11.21
• Domains: CLECT, EGF
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Complement and coagulation cascades
• MW: 60.4 kDa
• Gene Summary: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]